Version 5.4
Mus musculus Gene: Nudt18
Summary
InnateDB Gene IDBG-179072.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nudt18
Gene Name nudix (nucleoside diphosphate linked moiety X)-type motif 18
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000045211
Encoded Proteins
IDBP-179074
nudix (nucleoside diphosphate linked moiety X)-type motif 18
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules. This protein contains a Nudix hydrolase domain and hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates. [provided by RefSeq, Sep 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:70577847-70582571
Strand Forward strand
Band D2
Transcripts
ENSMUST00000089049 ENSMUSP00000086450
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Predicted by orthology
Total 32 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0044715 8-oxo-dGDP phosphatase activity
GO:0044716 8-oxo-GDP phosphatase activity
GO:0044717 8-hydroxy-dADP phosphatase activity
Biological Process
GO:0046057 dADP catabolic process
GO:0046067 dGDP catabolic process
GO:0046712 GDP catabolic process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
null
View Gene Order
ENSBTAG00000003483
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_196618
Phosphate bond hydrolysis by NUDT proteins pathway
REACT_245662
Metabolism of nucleotides pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q3U2V3
TrEMBL
UniProt Splice Variant
Entrez Gene 213484
UniGene Mm.34191
RefSeq NM_153136 XM_006518793
OMIM
CCDS CCDS27258
HPRD
IMGT
MGI ID MGI:2385853
MGI Symbol Nudt18
EMBL AK089446 AK145997 AK155086 AK157937 BC036718
GenPept AAH36718 BAC40887 BAE26818 BAE33037 BAE34271
RNA Seq Atlas 213484

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca