Version 5.4
Mus musculus Gene: Kcnj15
Summary
InnateDB Gene IDBG-179204.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcnj15
Gene Name potassium inwardly-rectifying channel, subfamily J, member 15
Synonyms 4930414N08Rik; AI182284; AI267127; IRKK; Kir4.2
Species Mus musculus
Ensembl Gene ENSMUSG00000062609
Encoded Proteins
IDBP-179206
potassium inwardly-rectifying channel, subfamily J, member 15
IDBP-252985
potassium inwardly-rectifying channel, subfamily J, member 15
IDBP-252987
potassium inwardly-rectifying channel, subfamily J, member 15
IDBP-252989
potassium inwardly-rectifying channel, subfamily J, member 15
IDBP-252991
potassium inwardly-rectifying channel, subfamily J, member 15
IDBP-252993
potassium inwardly-rectifying channel, subfamily J, member 15
IDBP-252995
potassium inwardly-rectifying channel, subfamily J, member 15
IDBP-252997
potassium inwardly-rectifying channel, subfamily J, member 15
IDBP-534097
potassium inwardly-rectifying channel, subfamily J, member 15
IDBP-532903
potassium inwardly-rectifying channel, subfamily J, member 15
IDBP-538384
potassium inwardly-rectifying channel, subfamily J, member 15
IDBP-538808
potassium inwardly-rectifying channel, subfamily J, member 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157551:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Eight transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:95257558-95300260
Strand Forward strand
Band C4
Transcripts
ENSMUST00000037154 ENSMUSP00000045218
ENSMUST00000113862 ENSMUSP00000109493
ENSMUST00000113861 ENSMUSP00000109492
ENSMUST00000113859 ENSMUSP00000109490
ENSMUST00000113858 ENSMUSP00000109489
ENSMUST00000113856 ENSMUSP00000109487
ENSMUST00000113855 ENSMUSP00000109486
ENSMUST00000113854 ENSMUSP00000109485
ENSMUST00000134166 ENSMUSP00000118992
ENSMUST00000125847 ENSMUSP00000114646
ENSMUST00000140222 ENSMUSP00000114449
ENSMUST00000152516
ENSMUST00000138329 ENSMUSP00000117744
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005242 inward rectifier potassium channel activity
GO:0005267 potassium channel activity
GO:0005515 protein binding
Biological Process
GO:0006813 potassium ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000157551
View Gene Order
ENSBTAG00000000973
Not yet available
Pathways
NETPATH
REACTOME
REACT_214393
Inwardly rectifying K+ channels pathway
REACT_208267
G protein gated Potassium channels pathway
REACT_203664
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_207065
Activation of GABAB receptors pathway
REACT_202800
Potassium Channels pathway
REACT_217868
GABA B receptor activation pathway
REACT_224131
GABA receptor activation pathway
REACT_259290
Neuronal System pathway
REACT_226457
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
REACT_233318
Transmission across Chemical Synapses pathway
REACT_208837
Activation of G protein gated Potassium channels pathway
KEGG
mmu04971
Gastric acid secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25004
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
REACT_25031
GABA B receptor activation pathway
REACT_75831
Activation of G protein gated Potassium channels pathway
REACT_13685
Neuronal System pathway
REACT_25199
GABA receptor activation pathway
REACT_75780
G protein gated Potassium channels pathway
REACT_25330
Activation of GABAB receptors pathway
REACT_75918
Inwardly rectifying K+ channels pathway
REACT_75908
Potassium Channels pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_15370
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
KEGG
hsa04971
Gastric acid secretion pathway
INOH
PID NCI
integrin_a9b1_pathway
Alpha9 beta1 integrin signaling events
Cross-References
SwissProt O88932
TrEMBL D3YV68 Q53Z04
UniProt Splice Variant
Entrez Gene 16516
UniGene Mm.272239 Mm.402992
RefSeq NM_001271689 XM_006522952 XM_006523190 XM_006523192 XM_006523193 NM_001039056 NM_001039057 NM_001271687 NM_001271690 NM_001271691 NM_001271692 NM_001271693 NM_001271694 NM_001271695 NM_019664 XM_006522942 XM_006522943 XM_006522944 XM_006522945 XM_006522947 XM_006522948 XM_006522949 XM_006522951 XM_006523173 XM_006523174 XM_006523175 XM_006523176 XM_006523177 XM_006523178 XM_006523179 XM_006523180 XM_006523182 XM_006523183 XM_006523184 XM_006523185 XM_006523186 XM_006523187 XM_006523188 XM_006523189 XM_006523191
OMIM
CCDS CCDS37410 CCDS28351
HPRD
IMGT
MGI ID MGI:1310000
MGI Symbol Kcnj15
EMBL AC154546 AC154691 AF085696 AJ012368 AJ300831 AK085689 AK165436 AY377988 BC010794 BC057915 BC138478 CH466602
GenPept AAC68685 AAH10794 AAH57915 AAI38479 AAQ88166 BAC39507 BAE38186 CAB89666 CAC83656 EDL03715 EDL03716
RNA Seq Atlas 16516

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca