Version 5.4
Mus musculus Gene: Mkrn2
Summary
InnateDB Gene IDBG-179379.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mkrn2
Gene Name makorin, ring finger protein, 2
Synonyms 2610002L04Rik; C81377
Species Mus musculus
Ensembl Gene ENSMUSG00000000439
Encoded Proteins
IDBP-179381
makorin, ring finger protein, 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075975:
This gene encodes a probable E3 ubiquitin ligase containing several zinc finger domains, that is a member of the makorin RING zinc-finger protein family. This gene overlaps the v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1) gene in an antisense orientation and may have a co-regulatory function with RAF1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:115601938-115618670
Strand Forward strand
Band E3
Transcripts
ENSMUST00000000449 ENSMUSP00000000449
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005622 intracellular
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000075975
View Gene Order
ENSBTAG00000004512
Not yet available
Cross-References
SwissProt Q9ERV1
TrEMBL
UniProt Splice Variant
Entrez Gene 67027
UniGene Mm.101316
RefSeq NM_023290
OMIM
CCDS CCDS39600
HPRD
IMGT
MGI ID MGI:1914277
MGI Symbol Mkrn2
EMBL AF277171 AK011295 AK077926 BC025547 CH466523
GenPept AAG27596 AAH25547 BAB27523 BAC37068 EDK99532
RNA Seq Atlas 67027

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca