Mus musculus Gene: Nfyb | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-179826.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Nfyb | ||||||||||||||||||||||
Gene Name | nuclear transcription factor-Y beta | ||||||||||||||||||||||
Synonyms | AA985999; Cbf-A | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000020248 | ||||||||||||||||||||||
Encoded Proteins |
nuclear transcription factor-Y beta
nuclear transcription factor-Y beta
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120837:
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 10:82748701-82764144 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | C1 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
ATF6-alpha activates chaperone genes pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Unfolded Protein Response (UPR) pathway
Metabolism pathway
Metabolism of proteins pathway
Metabolism of lipids and lipoproteins pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
PERK regulates gene expression pathway
ATF6-alpha activates chaperones pathway
PPARA activates gene expression pathway
ATF4 activates genes pathway
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KEGG |
Antigen processing and presentation pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH |
TGF_beta_Receptor pathway
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REACTOME |
ATF4 activates genes pathway
PERK regulates gene expression pathway
ATF6-alpha activates chaperone genes pathway
ATF6-alpha activates chaperones pathway
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Unfolded Protein Response (UPR) pathway
Metabolism of lipids and lipoproteins pathway
Metabolism of proteins pathway
Metabolism pathway
PERK regulates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
ATF4 activates genes pathway
ATF6-alpha activates chaperone genes pathway
Metabolism of proteins pathway
Metabolism of lipids and lipoproteins pathway
Activation of gene expression by SREBF (SREBP) pathway
Metabolism pathway
PPARA activates gene expression pathway
Unfolded Protein Response (UPR) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
ATF6-alpha activates chaperones pathway
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KEGG |
Antigen processing and presentation pathway
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INOH | |||||||||||||||||||||||
PID NCI |
Direct p53 effectors
Validated targets of C-MYC transcriptional repression
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Mm.245998 Mm.401568 Mm.465963 | ||||||||||||||||||||||
RefSeq | NM_010914 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS48654 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||