Mus musculus Gene: Polr3b | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-180612.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Polr3b | ||||||||||||
Gene Name | polymerase (RNA) III (DNA directed) polypeptide B | ||||||||||||
Synonyms | 2700078H01Rik; A330032P03Rik; C85372; RPC2 | ||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Gene | ENSMUSG00000034453 | ||||||||||||
Encoded Proteins |
polymerase (RNA) III (DNA directed) polypeptide B
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000013503:
This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 10:84622437-84727177 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | C1 | ||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Innate Immune System pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
RNA Polymerase III Transcription Initiation pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
Immune System pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
RNA Polymerase III Abortive And Retractive Initiation pathway
Cytosolic sensors of pathogen-associated DNA pathway
Gene Expression pathway
RNA Polymerase III Transcription Termination pathway
RNA Polymerase III Transcription pathway
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
RNA Polymerase III Chain Elongation pathway
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KEGG |
Pyrimidine metabolism pathway
RNA polymerase pathway
Purine metabolism pathway
Cytosolic DNA-sensing pathway pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
RNA Polymerase III Abortive And Retractive Initiation pathway
RNA Polymerase III Transcription Termination pathway
RNA Polymerase III Chain Elongation pathway
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase III Transcription Initiation pathway
Innate Immune System pathway
Immune System pathway
RNA Polymerase III Transcription pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Cytosolic sensors of pathogen-associated DNA pathway
Gene Expression pathway
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KEGG |
Pyrimidine metabolism pathway
Purine metabolism pathway
RNA polymerase pathway
Cytosolic DNA-sensing pathway pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | P59470 | ||||||||||||
TrEMBL | Q9CSL3 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 70428 | ||||||||||||
UniGene | Mm.335007 | ||||||||||||
RefSeq | NM_027423 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS24081 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
MGI ID | MGI:1917678 | ||||||||||||
MGI Symbol | Polr3b | ||||||||||||
EMBL | AK012532 AK039366 BC044796 BC068143 | ||||||||||||
GenPept | AAH44796 AAH68143 BAB28301 BAC30327 | ||||||||||||
RNA Seq Atlas | 70428 | ||||||||||||