Homo sapiens Gene: TAF4B | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-1811.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | TAF4B | ||||||||||||||||||
Gene Name | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | ||||||||||||||||||
Synonyms | SPGF13; TAF2C2; TAFII105 | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000141384 | ||||||||||||||||||
Encoded Proteins |
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
TATA binding protein (TBP) and TBP-associated factors (TAFs) participate in the formation of the TFIID protein complex, which is involved in initiation of transcription of genes by RNA polymerase II. This gene encodes a cell type-specific TAF that may be responsible for mediating transcription by a subset of activators in B cells. [provided by RefSeq, Sep 2011] TATA binding protein (TBP) and TBP-associated factors (TAFs) participate in the formation of the TFIID protein complex, which is involved in initiation of transcription of genes by RNA polymerase II. This gene encodes a cell type-specific TAF that may be responsible for mediating transcription by a subset of activators in B cells. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 18:26225936-26391685 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | q11.2 | ||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase II Pre-transcription Events pathway
RNA Polymerase II Promoter Escape pathway
RNA Polymerase II Transcription Initiation pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
HIV Transcription Initiation pathway
RNA Polymerase II HIV Promoter Escape pathway
Transcription of the HIV genome pathway
Late Phase of HIV Life Cycle pathway
RNA Polymerase II Transcription pathway
HIV Life Cycle pathway
HIV Infection pathway
Gene Expression pathway
Disease pathway
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KEGG |
Basal transcription factors pathway
Huntington's disease pathway
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INOH | |||||||||||||||||||
PID NCI |
Validated targets of C-MYC transcriptional activation
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Cross-References | |||||||||||||||||||
SwissProt | Q92750 | ||||||||||||||||||
TrEMBL | A4PBF8 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 6875 | ||||||||||||||||||
UniGene | Hs.369519 Hs.604391 | ||||||||||||||||||
RefSeq | NM_001293725 NM_005640 XM_005258339 XM_006722528 | ||||||||||||||||||
HUGO | HGNC:11538 | ||||||||||||||||||
OMIM | 601689 | ||||||||||||||||||
CCDS | CCDS42421 | ||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AB234097 AY888048 AY888049 Y09321 | ||||||||||||||||||
GenPept | AAX14897 AAX14898 BAF51562 CAA70499 | ||||||||||||||||||
RNA Seq Atlas | 6875 | ||||||||||||||||||