Version 5.4
Homo sapiens Gene: SNAP29
Summary
InnateDB Gene IDBG-1814.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNAP29
Gene Name synaptosomal-associated protein, 29kDa
Synonyms CEDNIK; SNAP-29
Species Homo sapiens
Ensembl Gene ENSG00000099940
Encoded Proteins
IDBP-1816
synaptosomal-associated protein, 29kDa
IDBP-364098
synaptosomal-associated protein, 29kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:20858983-20891218
Strand Forward strand
Band q11.21
Transcripts
ENST00000215730 ENSP00000215730
ENST00000439214 ENSP00000411095
ENST00000490458
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
Experimentally validated
Total 30 [view]
Protein-Protein 29 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
Biological Process
GO:0000046 autophagic vacuole fusion
GO:0006887 exocytosis
GO:0006903 vesicle targeting
GO:0015031 protein transport
GO:0061025 membrane fusion
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005886 plasma membrane
GO:0030054 cell junction
GO:0031201 SNARE complex
GO:0043005 neuron projection
GO:0045202 synapse
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022765
View Gene Order
ENSBTAG00000020760
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.108002 Hs.595327 Hs.701035
RefSeq NM_004782
HUGO
OMIM
CCDS CCDS13784
HPRD 11968
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca