Version 5.4
Mus musculus Gene: Prdm4
Summary
InnateDB Gene IDBG-181676.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prdm4
Gene Name PR domain containing 4
Synonyms 1700031E19Rik; 2810470D21Rik; AW552272; SC-1
Species Mus musculus
Ensembl Gene ENSMUSG00000035529
Encoded Proteins
IDBP-181678
PR domain containing 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110851:
The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:85891970-85916945
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000037646 ENSMUSP00000041942
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0032259 methylation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000110851
View Gene Order
ENSBTAG00000012999
Not yet available
Pathways
NETPATH
REACTOME
REACT_248921
Signalling by NGF pathway
REACT_188257
Signal Transduction pathway
REACT_210847
p75 NTR receptor-mediated signalling pathway
REACT_202086
p75NTR negatively regulates cell cycle via SC1 pathway
KEGG
mmu04722
Neurotrophin signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_13695
p75NTR negatively regulates cell cycle via SC1 pathway
REACT_11061
Signalling by NGF pathway
REACT_13776
p75 NTR receptor-mediated signalling pathway
REACT_111102
Signal Transduction pathway
KEGG
hsa04722
Neurotrophin signaling pathway pathway
INOH
PID NCI
p75ntrpathway
p75(NTR)-mediated signaling
Cross-References
SwissProt Q80V63
TrEMBL
UniProt Splice Variant
Entrez Gene 72843
UniGene Mm.25307 Mm.408696 Mm.475332
RefSeq NM_181650 XM_006514193 XM_006514194 XM_006514195 XM_006514196 XM_006514197
OMIM
CCDS CCDS24093
HPRD
IMGT
MGI ID MGI:1920093
MGI Symbol Prdm4
EMBL BC042516 BC139409
GenPept AAH42516 AAI39410
RNA Seq Atlas 72843

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca