Version 5.4
Mus musculus Gene: Sms
Summary
InnateDB Gene IDBG-181702.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sms
Gene Name spermine synthase
Synonyms AI427066; Gy; gyro; SpmST; SPMSY
Species Mus musculus
Ensembl Gene ENSMUSG00000071708
Encoded Proteins
IDBP-255821
spermine synthase
IDBP-626081
spermine synthase
IDBP-539526
spermine synthase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102172:
This gene encodes a protein belonging to the spermidine/spermin synthase family. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene are associated with X-linked Snyder-Robinson mental retardation syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome X:157443855-157492287
Strand Reverse strand
Band F4
Transcripts
ENSMUST00000112529 ENSMUSP00000108148
ENSMUST00000145477 ENSMUSP00000131254
ENSMUST00000146026
ENSMUST00000127089
ENSMUST00000123770 ENSMUSP00000115810
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016768 spermine synthase activity
Biological Process
GO:0006597 spermine biosynthetic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000102172
View Gene Order
ENSBTAG00000018382
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
REACT_253147
Metabolism of polyamines pathway
KEGG
mmu00410
beta-Alanine metabolism pathway
mmu00480
Glutathione metabolism pathway
mmu00330
Arginine and proline metabolism pathway
mmu00270
Cysteine and methionine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_14820
Metabolism of polyamines pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
REACT_226362
Metabolism of amino acids and derivatives pathway
REACT_219139
Metabolism pathway
REACT_215919
Metabolism of polyamines pathway
KEGG
hsa00330
Arginine and proline metabolism pathway
hsa00480
Glutathione metabolism pathway
hsa00410
beta-Alanine metabolism pathway
hsa00270
Cysteine and methionine metabolism pathway
INOH
INOH website
Arginine Proline metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.18652 Mm.393741 Mm.399822 Mm.410914 Mm.462155
RefSeq NM_009214 XM_001473434 XM_006544569
OMIM
CCDS CCDS41189
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca