Version 5.4
Mus musculus Gene: Bnip2
Summary
InnateDB Gene IDBG-181773.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bnip2
Gene Name BCL2/adenovirus E1B interacting protein 2
Synonyms 5730523P12Rik; BNIP2beta; Nip21
Species Mus musculus
Ensembl Gene ENSMUSG00000011958
Encoded Proteins
IDBP-181775
BCL2/adenovirus E1B interacting protein 2
IDBP-181777
BCL2/adenovirus E1B interacting protein 2
IDBP-400741
BCL2/adenovirus E1B interacting protein 2
IDBP-535533
BCL2/adenovirus E1B interacting protein 2
IDBP-535074
BCL2/adenovirus E1B interacting protein 2
IDBP-622891
BCL2/adenovirus E1B interacting protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140299:
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. [provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:69989466-70008317
Strand Forward strand
Band D
Transcripts
ENSMUST00000034754 ENSMUSP00000034754
ENSMUST00000085393 ENSMUSP00000082513
ENSMUST00000117450 ENSMUSP00000113466
ENSMUST00000154772 ENSMUSP00000117957
ENSMUST00000143049
ENSMUST00000133307
ENSMUST00000137472 ENSMUSP00000115106
ENSMUST00000165389 ENSMUSP00000133200
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0001824 blastocyst development
GO:0006915 apoptotic process
GO:0043410 positive regulation of MAPK cascade
GO:0045666 positive regulation of neuron differentiation
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0051146 striated muscle cell differentiation
GO:0051297 centrosome organization
Cellular Component
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005814 centriole
GO:0005829 cytosol
GO:0031616 spindle pole centrosome
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000140299
View Gene Order
ENSBTAG00000013493
Not yet available
Pathways
NETPATH
REACTOME
REACT_253473
Myogenesis pathway
REACT_258600
CDO in myogenesis pathway
REACT_188576
Developmental Biology pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_21402
CDO in myogenesis pathway
REACT_111045
Developmental Biology pathway
REACT_21303
Myogenesis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q91VL0
UniProt Splice Variant
Entrez Gene 12175
UniGene Mm.159777 Mm.444586 Mm.487848
RefSeq NM_001008238 NM_016787 XM_006510791 XM_006510792 XM_006510793 XM_006510794
OMIM
CCDS CCDS23318 CCDS23319
HPRD
IMGT
MGI ID MGI:109327
MGI Symbol Bnip2
EMBL AC137108 AK169609 AY591757 BC012670 CH466522
GenPept AAH12670 AAT92039 BAE41257 EDL26177
RNA Seq Atlas 12175

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca