Version 5.4
| Mus musculus Gene: Gtf2a2 | |||||||||||||||||
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| Summary | |||||||||||||||||
| InnateDB Gene | IDBG-181923.6 | ||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
| Gene Symbol | Gtf2a2 | ||||||||||||||||
| Gene Name | general transcription factor II A, 2 | ||||||||||||||||
| Synonyms | |||||||||||||||||
| Species | Mus musculus | ||||||||||||||||
| Ensembl Gene | ENSMUSG00000033543 | ||||||||||||||||
| Encoded Proteins |
general transcription factor II A, 2
general transcription factor II A, 2
general transcription factor II A, 2
general transcription factor II A, 2
general transcription factor II A, 2
general transcription factor II A, 2
general transcription factor II A, 2
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| Protein Structure | |||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
| Entrez Gene | |||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140307:
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||||||||||||||
| Type | Protein coding | ||||||||||||||||
| Genomic Location | Chromosome 9:70012550-70022866 | ||||||||||||||||
| Strand | Forward strand | ||||||||||||||||
| Band | D | ||||||||||||||||
| Transcripts | |||||||||||||||||
| Interactions | |||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||
| NETPATH | |||||||||||||||||
| REACTOME |
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
RNA Polymerase II Transcription Initiation pathway
RNA Polymerase II Promoter Escape pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase II Pre-transcription Events pathway
Gene Expression pathway
RNA Polymerase II Transcription pathway
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| KEGG |
Basal transcription factors pathway
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| INOH | |||||||||||||||||
| PID NCI | |||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||
| NETPATH | |||||||||||||||||
| REACTOME |
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase II Pre-transcription Events pathway
RNA Polymerase II Promoter Escape pathway
RNA Polymerase II Transcription Initiation pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
HIV Transcription Initiation pathway
RNA Polymerase II HIV Promoter Escape pathway
Transcription of the HIV genome pathway
Late Phase of HIV Life Cycle pathway
RNA Polymerase II Transcription pathway
HIV Life Cycle pathway
HIV Infection pathway
Gene Expression pathway
Disease pathway
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| KEGG |
Basal transcription factors pathway
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| INOH | |||||||||||||||||
| PID NCI | |||||||||||||||||
| Cross-References | |||||||||||||||||
| SwissProt | |||||||||||||||||
| TrEMBL | |||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||
| Entrez Gene | |||||||||||||||||
| UniGene | Mm.293117 Mm.472948 | ||||||||||||||||
| RefSeq | NM_001039519 NM_001282083 NM_001282084 XM_006542887 | ||||||||||||||||
| OMIM | |||||||||||||||||
| CCDS | CCDS52851 CCDS72269 | ||||||||||||||||
| HPRD | |||||||||||||||||
| IMGT | |||||||||||||||||
| MGI ID | |||||||||||||||||
| MGI Symbol | |||||||||||||||||
| EMBL | |||||||||||||||||
| GenPept | |||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||