Version 5.4
| Mus musculus Gene: Timp3 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-182023.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Timp3 | ||||||||
| Gene Name | tissue inhibitor of metalloproteinase 3 | ||||||||
| Synonyms | Timp-3 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000020044 | ||||||||
| Encoded Proteins |
tissue inhibitor of metalloproteinase 3
tissue inhibitor of metalloproteinase 3
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100234:
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008] This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby\'s fundus dystrophy. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 10:86300372-86349506 | ||||||||
| Strand | Forward strand | ||||||||
| Band | C1 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||
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| REACTOME | |||||||||
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| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Mm.444873 Mm.447674 Mm.453558 Mm.4871 | ||||||||
| RefSeq | NM_011595 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS24097 | ||||||||
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| RNA Seq Atlas | |||||||||