Version 5.4
Mus musculus Gene: Gpx8
Summary
InnateDB Gene IDBG-183441.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpx8
Gene Name glutathione peroxidase 8 (putative)
Synonyms 2310016C16Rik; AU017063
Species Mus musculus
Ensembl Gene ENSMUSG00000021760
Encoded Proteins
IDBP-183443
glutathione peroxidase 8 (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164294:
Gene Information
Type Protein coding
Genomic Location Chromosome 13:113042763-113046388
Strand Reverse strand
Band D2.2
Transcripts
ENSMUST00000022282 ENSMUSP00000022282
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004601 peroxidase activity
GO:0004602 glutathione peroxidase activity
GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006979 response to oxidative stress
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000164294
View Gene Order
ENSBTAG00000021960
Not yet available
Pathways
NETPATH
REACTOME
REACT_188957
Cellular responses to stress pathway
REACT_189141
Detoxification of Reactive Oxygen Species pathway
KEGG
mmu00480
Glutathione metabolism pathway
mmu00590
Arachidonic acid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120956
Cellular responses to stress pathway
REACT_172715
Detoxification of Reactive Oxygen Species pathway
REACT_206069
Cellular responses to stress pathway
REACT_204534
Detoxification of Reactive Oxygen Species pathway
KEGG
hsa00590
Arachidonic acid metabolism pathway
hsa00480
Glutathione metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.12715
RefSeq NM_027127 XM_006517755
OMIM
CCDS CCDS26781
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca