Version 5.4
Homo sapiens Gene: AIFM3
Summary
InnateDB Gene IDBG-1846.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AIFM3
Gene Name apoptosis-inducing factor, mitochondrion-associated, 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000183773
Encoded Proteins
IDBP-231247
apoptosis-inducing factor, mitochondrion-associated, 3
IDBP-231249
apoptosis-inducing factor, mitochondrion-associated, 3
IDBP-292638
apoptosis-inducing factor, mitochondrion-associated, 3
IDBP-364270
apoptosis-inducing factor, mitochondrion-associated, 3
IDBP-364272
apoptosis-inducing factor, mitochondrion-associated, 3
IDBP-364273
apoptosis-inducing factor, mitochondrion-associated, 3
IDBP-364275
apoptosis-inducing factor, mitochondrion-associated, 3
IDBP-364286
apoptosis-inducing factor, mitochondrion-associated, 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:20965108-20981360
Strand Forward strand
Band q11.21
Transcripts
ENST00000399167 ENSP00000382120
ENST00000399163 ENSP00000382116
ENST00000405089 ENSP00000385800
ENST00000417515 ENSP00000412973
ENST00000441376 ENSP00000402067
ENST00000434714 ENSP00000399657
ENST00000426113 ENSP00000406989
ENST00000440238 ENSP00000390798
ENST00000467926
ENST00000479523
ENST00000472575
ENST00000495869
ENST00000468124
ENST00000484206
ENST00000496097
ENST00000465606
ENST00000483107
ENST00000486003
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050660 flavin adenine dinucleotide binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
GO:0097194 execution phase of apoptosis
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005783 endoplasmic reticulum
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022763
View Gene Order
ENSBTAG00000038132
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.723246 Hs.739104
RefSeq NM_001018060 NM_001146288 NM_144704
HUGO
OMIM
CCDS CCDS13786 CCDS33605 CCDS54503
HPRD 08085
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca