Homo sapiens Gene: SLC6A11 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-18491.6 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | SLC6A11 | ||||||||||||||||
Gene Name | solute carrier family 6 (neurotransmitter transporter, GABA), member 11 | ||||||||||||||||
Synonyms | GAT-3; GAT3; GAT4 | ||||||||||||||||
Species | Homo sapiens | ||||||||||||||||
Ensembl Gene | ENSG00000132164 | ||||||||||||||||
Encoded Proteins |
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABAergic neurotransmission is terminated by the uptake of GABA into the presynaptic terminal and the surrounding astroglial cells by sodium-dependent transporters, such as SLC6A11 (Borden et al., 1994 [PubMed 7874447]).[supplied by OMIM, Nov 2010] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 3:10816200-10940733 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | p25.3 | ||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
Na+/Cl- dependent neurotransmitter transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Creatine metabolism pathway
Reuptake of GABA pathway
GABA synthesis, release, reuptake and degradation pathway
Transmembrane transport of small molecules pathway
Neuronal System pathway
Metabolism of amino acids and derivatives pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Release Cycle pathway
Metabolism pathway
SLC-mediated transmembrane transport pathway
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KEGG | |||||||||||||||||
INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | |||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | |||||||||||||||||
UniGene | Hs.101791 Hs.657405 | ||||||||||||||||
RefSeq | NM_014229 | ||||||||||||||||
HUGO | |||||||||||||||||
OMIM | |||||||||||||||||
CCDS | CCDS2602 | ||||||||||||||||
HPRD | 06406 | ||||||||||||||||
IMGT | |||||||||||||||||
EMBL | |||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | |||||||||||||||||