Mus musculus Gene: Kcna2 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-185044.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Kcna2 | ||||||||||||||||||||||
Gene Name | potassium voltage-gated channel, shaker-related subfamily, member 2 | ||||||||||||||||||||||
Synonyms | Akr6a4; ENSMUSG00000074335; Gm10672; Kca1-2; Kv1.2; Mk-2 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000040724 | ||||||||||||||||||||||
Encoded Proteins |
potassium voltage-gated channel, shaker-related subfamily, member 2
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177301:
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 3:107101567-107106879 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | F2.3 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Potassium Channels pathway
Neuronal System pathway
Voltage gated Potassium channels pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Voltage gated Potassium channels pathway
Neuronal System pathway
Potassium Channels pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | P63141 | ||||||||||||||||||||||
TrEMBL | B2RS05 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 16490 | ||||||||||||||||||||||
UniGene | Mm.39285 Mm.397905 Mm.56930 | ||||||||||||||||||||||
RefSeq | NM_008417 XM_006501048 XM_006501049 XM_006501050 XM_006501051 XM_006501052 XM_006501053 XM_006501054 XM_006501055 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS17733 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:96659 | ||||||||||||||||||||||
MGI Symbol | Kcna2 | ||||||||||||||||||||||
EMBL | AK044342 BC138650 BC138651 CH466607 M30440 | ||||||||||||||||||||||
GenPept | AAA39713 AAI38651 AAI38652 BAC31877 EDL01892 | ||||||||||||||||||||||
RNA Seq Atlas | 16490 | ||||||||||||||||||||||