Version 5.4
Homo sapiens Gene: LZTR1
Summary
InnateDB Gene IDBG-1851.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LZTR1
Gene Name leucine-zipper-like transcription regulator 1
Synonyms BTBD29; LZTR-1; SWNTS2
Species Homo sapiens
Ensembl Gene ENSG00000099949
Encoded Proteins
IDBP-1853
leucine-zipper-like transcription regulator 1
IDBP-1855
leucine-zipper-like transcription regulator 1
IDBP-364396
leucine-zipper-like transcription regulator 1
IDBP-364402
leucine-zipper-like transcription regulator 1
IDBP-364414
leucine-zipper-like transcription regulator 1
IDBP-364417
leucine-zipper-like transcription regulator 1
IDBP-364419
leucine-zipper-like transcription regulator 1
IDBP-364420
leucine-zipper-like transcription regulator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:20979462-20999038
Strand Forward strand
Band q11.21
Transcripts
ENST00000215739 ENSP00000215739
ENST00000389355 ENSP00000374006
ENST00000414985 ENSP00000397247
ENST00000443265 ENSP00000406466
ENST00000415354 ENSP00000393765
ENST00000439171 ENSP00000390836
ENST00000452988 ENSP00000408789
ENST00000415817 ENSP00000397252
ENST00000479606
ENST00000493460
ENST00000480895
ENST00000497716
ENST00000461510
ENST00000492480
ENST00000495142
ENST00000491432
ENST00000464807
ENST00000463909
ENST00000498649
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
Experimentally validated
Total 55 [view]
Protein-Protein 52 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0009653 anatomical structure morphogenesis
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022761
View Gene Order
ENSBTAG00000011292
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 8216
UniGene Hs.78788
RefSeq NM_006767
HUGO HGNC:6742
OMIM 600574
CCDS CCDS33606
HPRD 08992
IMGT
EMBL
GenPept
RNA Seq Atlas 8216

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca