Version 5.4
| Mus musculus Gene: Slc4a8 | |||||||||||||||
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| Summary | |||||||||||||||
| InnateDB Gene | IDBG-185143.6 | ||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
| Gene Symbol | Slc4a8 | ||||||||||||||
| Gene Name | solute carrier family 4 (anion exchanger), member 8 | ||||||||||||||
| Synonyms | AW493845; C230026C11; kNBC-3; NDCBE | ||||||||||||||
| Species | Mus musculus | ||||||||||||||
| Ensembl Gene | ENSMUSG00000023032 | ||||||||||||||
| Encoded Proteins |
solute carrier family 4 (anion exchanger), member 8
solute carrier family 4 (anion exchanger), member 8
solute carrier family 4 (anion exchanger), member 8
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| Protein Structure | |||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
| Entrez Gene | |||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000050438:
The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4\'-Di-isothiocyanatostilbene-2,2\'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
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| Gene Information | |||||||||||||||
| Type | Protein coding | ||||||||||||||
| Genomic Location | Chromosome 15:100761747-100823968 | ||||||||||||||
| Strand | Forward strand | ||||||||||||||
| Band | F1 | ||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||
| NETPATH | |||||||||||||||
| REACTOME |
SLC-mediated transmembrane transport pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Bicarbonate transporters pathway
Transmembrane transport of small molecules pathway
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| KEGG | |||||||||||||||
| INOH | |||||||||||||||
| PID NCI | |||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||
| NETPATH | |||||||||||||||
| REACTOME |
Bicarbonate transporters pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
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| KEGG | |||||||||||||||
| INOH | |||||||||||||||
| PID NCI | |||||||||||||||
| Cross-References | |||||||||||||||
| SwissProt | |||||||||||||||
| TrEMBL | E0CYV1 | ||||||||||||||
| UniProt Splice Variant | |||||||||||||||
| Entrez Gene | 59033 | ||||||||||||||
| UniGene | Mm.209856 Mm.408499 | ||||||||||||||
| RefSeq | NM_021530 XM_006521225 XM_006521226 | ||||||||||||||
| OMIM | |||||||||||||||
| CCDS | CCDS37214 | ||||||||||||||
| HPRD | |||||||||||||||
| IMGT | |||||||||||||||
| MGI ID | MGI:1928745 | ||||||||||||||
| MGI Symbol | Slc4a8 | ||||||||||||||
| EMBL | AC113587 | ||||||||||||||
| GenPept | |||||||||||||||
| RNA Seq Atlas | 59033 | ||||||||||||||