Version 5.4
Mus musculus Gene: Kcnc4
Summary
InnateDB Gene IDBG-185226.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcnc4
Gene Name potassium voltage gated channel, Shaw-related subfamily, member 4
Synonyms AI850292; Kcr2-4; KSHIIIC; Kv3.4
Species Mus musculus
Ensembl Gene ENSMUSG00000027895
Encoded Proteins
IDBP-185228
potassium voltage gated channel, Shaw-related subfamily, member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116396:
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:107438303-107458898
Strand Reverse strand
Band F2.3
Transcripts
ENSMUST00000009617 ENSMUSP00000009617
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005515 protein binding
Biological Process
GO:0006811 ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0046928 regulation of neurotransmitter secretion
GO:0051260 protein homooligomerization
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
GO:0031594 neuromuscular junction
GO:0043679 axon terminus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000116396
View Gene Order
ENSBTAG00000007352
Not yet available
Pathways
NETPATH
REACTOME
REACT_202800
Potassium Channels pathway
REACT_259290
Neuronal System pathway
REACT_199077
Voltage gated Potassium channels pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75770
Voltage gated Potassium channels pathway
REACT_13685
Neuronal System pathway
REACT_75908
Potassium Channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8R1C0
TrEMBL
UniProt Splice Variant
Entrez Gene 99738
UniGene Mm.101976
RefSeq NM_145922
OMIM
CCDS CCDS17738
HPRD
IMGT
MGI ID MGI:96670
MGI Symbol Kcnc4
EMBL BC024837
GenPept AAH24837
RNA Seq Atlas 99738

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca