Version 5.4
Mus musculus Gene: Serpinb5
Summary
InnateDB Gene IDBG-185824.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Serpinb5
Gene Name serine (or cysteine) peptidase inhibitor, clade B, member 5
Synonyms 1110036M19Rik; AI462524; AI646751; Maspin; ovalbumin; PI-5; Spi7
Species Mus musculus
Ensembl Gene ENSMUSG00000067006
Encoded Proteins
IDBP-185826
serine (or cysteine) peptidase inhibitor, clade B, member 5
IDBP-255391
serine (or cysteine) peptidase inhibitor, clade B, member 5
IDBP-255393
serine (or cysteine) peptidase inhibitor, clade B, member 5
IDBP-789459
serine (or cysteine) peptidase inhibitor, clade B, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000206075:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:106861173-106883348
Strand Forward strand
Band E2.1
Transcripts
ENSMUST00000086701 ENSMUSP00000083908
ENSMUST00000112730 ENSMUSP00000108350
ENSMUST00000112729 ENSMUSP00000108349
ENSMUST00000188745 ENSMUSP00000140264
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0002009 morphogenesis of an epithelium
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
GO:0030198 extracellular matrix organization
GO:0050678 regulation of epithelial cell proliferation
GO:0060512 prostate gland morphogenesis
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000206075
View Gene Order
ENSBTAG00000002019
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04115
p53 signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04115
p53 signaling pathway pathway
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
atf2_pathway
ATF-2 transcription factor network
tap63pathway
Validated transcriptional targets of TAp63 isoforms
Cross-References
SwissProt P70124
TrEMBL
UniProt Splice Variant
Entrez Gene 20724
UniGene Mm.268618 Mm.436502
RefSeq NM_009257 XM_006529290 XM_006529291
OMIM
CCDS CCDS35684
HPRD
IMGT
MGI ID MGI:109579
MGI Symbol Serpinb5
EMBL AK136532 AK145220 BC005434 CH466520 U54705
GenPept AAB06042 AAH05434 BAE23032 BAE26308 EDL39856 EDL39857
RNA Seq Atlas 20724

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca