Version 5.4
Mus musculus Gene: Ampd2
Summary
InnateDB Gene IDBG-186141.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ampd2
Gene Name adenosine monophosphate deaminase 2
Synonyms 1200014F01Rik; AI552571; Ampd-2
Species Mus musculus
Ensembl Gene ENSMUSG00000027889
Encoded Proteins
IDBP-186143
adenosine monophosphate deaminase 2
IDBP-186145
adenosine monophosphate deaminase 2
IDBP-186147
adenosine monophosphate deaminase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116337:
The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:108074062-108086651
Strand Reverse strand
Band F2.3
Transcripts
ENSMUST00000102638 ENSMUSP00000099698
ENSMUST00000102637 ENSMUSP00000099697
ENSMUST00000078912 ENSMUSP00000077946
ENSMUST00000106667
ENSMUST00000127232
ENSMUST00000125467
ENSMUST00000136712
ENSMUST00000149479
ENSMUST00000133129
ENSMUST00000153626
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003876 AMP deaminase activity
GO:0019239 deaminase activity
GO:0046872 metal ion binding
Biological Process
GO:0006188 IMP biosynthetic process
GO:0009117 nucleotide metabolic process
GO:0032264 IMP salvage
GO:0052652 cyclic purine nucleotide metabolic process
GO:0097009 energy homeostasis
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000116337
View Gene Order
ENSBTAG00000013018
Not yet available
Pathways
NETPATH
REACTOME
REACT_263730
Purine metabolism pathway
REACT_188937
Metabolism pathway
REACT_244050
Purine salvage pathway
REACT_245662
Metabolism of nucleotides pathway
KEGG
mmu00230
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1923
Purine salvage pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_522
Purine metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.274335
RefSeq NM_001289719 NM_028779 XM_006500868 XM_006500871
OMIM
CCDS CCDS17749
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca