Version 5.4
Mus musculus Gene: Abcc10
Summary
InnateDB Gene IDBG-186816.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abcc10
Gene Name ATP-binding cassette, sub-family C (CFTR/MRP), member 10
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000032842
Encoded Proteins
IDBP-186818
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
IDBP-186820
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
IDBP-624234
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
IDBP-624237
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
IDBP-624240
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:46303221-46328352
Strand Reverse strand
Band C
Transcripts
ENSMUST00000047970 ENSMUSP00000038041
ENSMUST00000095261 ENSMUSP00000092895
ENSMUST00000167360 ENSMUSP00000131843
ENSMUST00000171584 ENSMUSP00000132561
ENSMUST00000168490 ENSMUSP00000132760
ENSMUST00000165733
ENSMUST00000170168
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Biological Process
GO:0006200 ATP catabolic process
GO:0006810 transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124574
View Gene Order
ENSBTAG00000005842
Not yet available
Pathways
NETPATH
REACTOME
REACT_253400
Transmembrane transport of small molecules pathway
REACT_237882
ABC-family proteins mediated transport pathway
KEGG
mmu02010
ABC transporters pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15480
ABC-family proteins mediated transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
KEGG
hsa02010
ABC transporters pathway
INOH
PID NCI
Cross-References
SwissProt Q8R4P9
TrEMBL
UniProt Splice Variant
Entrez Gene 224814
UniGene
RefSeq XM_006524142 NM_145140 NM_170680 XM_006524143
OMIM
CCDS CCDS28825 CCDS50124
HPRD
IMGT
MGI ID MGI:2386976
MGI Symbol Abcc10
EMBL AF406642 AF417121 AK133240 AK170600
GenPept AAM18535 AAM18536 BAE21573 BAE41905
RNA Seq Atlas 224814

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca