Version 5.4
Mus musculus Gene: Glmn
Summary
InnateDB Gene IDBG-187045.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Glmn
Gene Name glomulin, FKBP associated protein
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029276
Encoded Proteins
IDBP-187047
glomulin, FKBP associated protein
IDBP-187049
glomulin, FKBP associated protein
IDBP-187051
glomulin, FKBP associated protein
IDBP-538274
glomulin, FKBP associated protein
IDBP-540748
glomulin, FKBP associated protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174842:
This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:107548967-107597888
Strand Reverse strand
Band E5
Transcripts
ENSMUST00000082121 ENSMUSP00000080766
ENSMUST00000078021 ENSMUSP00000077168
ENSMUST00000100949 ENSMUSP00000098509
ENSMUST00000137939
ENSMUST00000124546 ENSMUSP00000122129
ENSMUST00000148505
ENSMUST00000143113
ENSMUST00000124140 ENSMUSP00000123224
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005171 hepatocyte growth factor receptor binding
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0055105 ubiquitin-protein transferase inhibitor activity
Biological Process
GO:0001570 vasculogenesis
GO:0001843 neural tube closure
GO:0031397 negative regulation of protein ubiquitination
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0040029 regulation of gene expression, epigenetic
GO:0042130 negative regulation of T cell proliferation
GO:0042327 positive regulation of phosphorylation
GO:0042692 muscle cell differentiation
GO:0045086 positive regulation of interleukin-2 biosynthetic process
GO:0050715 positive regulation of cytokine secretion
GO:0072359 circulatory system development
Cellular Component
GO:0031461 cullin-RING ubiquitin ligase complex
GO:0031462 Cul2-RING ubiquitin ligase complex
GO:0031463 Cul3-RING ubiquitin ligase complex
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000174842
View Gene Order
ENSBTAG00000018737
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.41417
RefSeq NM_001161738 NM_001161739 NM_133248 XM_006534800
OMIM
CCDS CCDS19505 CCDS51587
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca