Mus musculus Gene: Cradd | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-187068.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Cradd | ||||||||||||
Gene Name | CASP2 and RIPK1 domain containing adaptor with death domain | ||||||||||||
Synonyms | RAIDD | ||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Gene | ENSMUSG00000045867 | ||||||||||||
Encoded Proteins |
CASP2 and RIPK1 domain containing adaptor with death domain
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169372:
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 10:95174746-95324097 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | C2 | ||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH |
TNFalpha pathway
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REACTOME | |||||||||||||
KEGG | |||||||||||||
INOH | |||||||||||||
PID NCI |
Ceramide signaling pathway
Caspase Cascade in Apoptosis
HIV-1 Nef: Negative effector of Fas and TNF-alpha
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Cross-References | |||||||||||||
SwissProt | O88843 | ||||||||||||
TrEMBL | Q549T4 Q9QWR7 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 12905 | ||||||||||||
UniGene | |||||||||||||
RefSeq | NM_009950 XM_006513178 XM_006513179 XM_006513180 XM_006513181 XM_006513182 XM_006513185 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS24135 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
MGI ID | MGI:1336168 | ||||||||||||
MGI Symbol | Cradd | ||||||||||||
EMBL | AE016773 AF017992 AJ224738 AJ224739 AJ224740 AK136561 AK163112 BC005608 CH466539 | ||||||||||||
GenPept | AAC35882 AAH05608 AAN84619 BAE23045 BAE37198 CAA12107 CAA12108 CAA12109 EDL21592 EDL21593 EDL21595 EDL21596 | ||||||||||||
RNA Seq Atlas | 12905 | ||||||||||||