Version 5.4
Mus musculus Gene: Eea1
Summary
InnateDB Gene IDBG-187255.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eea1
Gene Name early endosome antigen 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000036499
Encoded Proteins
IDBP-187257
early endosome antigen 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102189:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:95940663-96045518
Strand Forward strand
Band C2
Transcripts
ENSMUST00000053484 ENSMUSP00000061493
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005545 1-phosphatidylinositol binding
GO:0030742 GTP-dependent protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006897 endocytosis
GO:0006906 vesicle fusion
Cellular Component
GO:0005768 endosome
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005969 serine-pyruvate aminotransferase complex
GO:0019897 extrinsic component of plasma membrane
GO:0031410 cytoplasmic vesicle
GO:0031901 early endosome membrane
GO:0044308 axonal spine
GO:0055037 recycling endosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000102189
View Gene Order
ENSBTAG00000000421
Not yet available
Pathways
NETPATH
REACTOME
REACT_239142
Innate Immune System pathway
REACT_230745
Immune System pathway
REACT_249409
Toll Like Receptor 9 (TLR9) Cascade pathway
REACT_251547
Toll-Like Receptors Cascades pathway
KEGG
mmu04144
Endocytosis pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_9047
Toll Like Receptor 9 (TLR9) Cascade pathway
REACT_6802
Innate Immune System pathway
REACT_6966
Toll-Like Receptors Cascades pathway
REACT_6900
Immune System pathway
KEGG
hsa04144
Endocytosis pathway
hsa04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt Q8BL66
TrEMBL
UniProt Splice Variant
Entrez Gene 216238
UniGene Mm.401732 Mm.490373
RefSeq NM_001001932 XM_006513522 XM_006513523 XM_006513524 XM_006513525
OMIM
CCDS CCDS36042
HPRD
IMGT
MGI ID MGI:2442192
MGI Symbol Eea1
EMBL AK046231 BC075637
GenPept AAH75637 BAC32647
RNA Seq Atlas 216238

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca