Version 5.4
Mus musculus Gene: Fhod1
Summary
InnateDB Gene IDBG-187431.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fhod1
Gene Name formin homology 2 domain containing 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000014778
Encoded Proteins
IDBP-187433
formin homology 2 domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135723:
This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:105329163-105347953
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000014922 ENSMUSP00000014922
ENSMUST00000132777
ENSMUST00000134837
ENSMUST00000136439
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005488 binding
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051496 positive regulation of stress fiber assembly
Cellular Component
GO:0001725 stress fiber
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:0032059 bleb
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135723
View Gene Order
ENSBTAG00000032427
Not yet available
Cross-References
SwissProt Q6P9Q4
TrEMBL
UniProt Splice Variant
Entrez Gene 234686
UniGene
RefSeq NM_177699
OMIM
CCDS CCDS22600
HPRD
IMGT
MGI ID MGI:2679008
MGI Symbol Fhod1
EMBL AB041045 AK030737 BC060654
GenPept AAH60654 BAC27106 BAE06182
RNA Seq Atlas 234686

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca