Mus musculus Gene: Slc6a5 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-188115.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Slc6a5 | ||||||||
Gene Name | solute carrier family 6 (neurotransmitter transporter, glycine), member 5 | ||||||||
Synonyms | Glyt2; prestin | ||||||||
Species | Mus musculus | ||||||||
Ensembl Gene | ENSMUSG00000039728 | ||||||||
Encoded Proteins |
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165970:
This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. [provided by RefSeq, Oct 2009] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 7:49910146-49963856 | ||||||||
Strand | Forward strand | ||||||||
Band | B4 | ||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathway Predictions based on Human Orthology Data | |||||||||
NETPATH | |||||||||
REACTOME |
Na+/Cl- dependent neurotransmitter transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
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KEGG | |||||||||
INOH | |||||||||
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Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | |||||||||
UniGene | Mm.207053 Mm.409963 | ||||||||
RefSeq | NM_001146013 NM_148931 XM_006540545 XM_006540546 XM_006540547 XM_006540548 | ||||||||
OMIM | |||||||||
CCDS | CCDS21308 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
MGI ID | |||||||||
MGI Symbol | |||||||||
EMBL | |||||||||
GenPept | |||||||||
RNA Seq Atlas | |||||||||