Version 5.4
Mus musculus Gene: Slc6a15
Summary
InnateDB Gene IDBG-188450.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc6a15
Gene Name solute carrier family 6 (neurotransmitter transporter), member 15
Synonyms AA536730; AI326450; AI326451; v7-3
Species Mus musculus
Ensembl Gene ENSMUSG00000019894
Encoded Proteins
IDBP-188452
solute carrier family 6 (neurotransmitter transporter), member 15
IDBP-712782
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000072041:
This gene encodes a member of the solute carrier family 6 protein family which transports neutral amino acids. The encoded protein is thought to play a role in neuronal amino acid transport (PMID: 16185194) and may be associated with major depression (PMID: 21521612). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:103367808-103419378
Strand Forward strand
Band D1
Transcripts
ENSMUST00000074204 ENSMUSP00000073829
ENSMUST00000179636 ENSMUSP00000136676
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005298 proline:sodium symporter activity
GO:0005328 neurotransmitter:sodium symporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0006836 neurotransmitter transport
GO:0015804 neutral amino acid transport
GO:0015820 leucine transport
GO:0015824 proline transport
GO:0035524 proline transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000072041
View Gene Order
ENSBTAG00000018432
Not yet available
Pathways
NETPATH
REACTOME
REACT_217615
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_251788
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_253228
Na+/Cl- dependent neurotransmitter transporters pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_230460
Amino acid transport across the plasma membrane pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20506
Na+/Cl- dependent neurotransmitter transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_222460
SLC-mediated transmembrane transport pathway
REACT_223103
Transmembrane transport of small molecules pathway
REACT_203377
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_202360
Amino acid transport across the plasma membrane pathway
REACT_206645
Na+/Cl- dependent neurotransmitter transporters pathway
REACT_212003
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8BG16
TrEMBL Q8R0C2
UniProt Splice Variant
Entrez Gene 103098
UniGene Mm.400409 Mm.458408
RefSeq NM_001252330 NM_175328 XM_006512983 XM_006512984
OMIM
CCDS CCDS24156
HPRD
IMGT
MGI ID MGI:2143484
MGI Symbol Slc6a15
EMBL AK036136 AM085111 AY149280 AY149281 AY149282 BC027078 BC076593 CH466539
GenPept AAH27078 AAH76593 AAN75437 AAN75438 AAN75439 BAC29315 CAJ29896 EDL21676 EDL21677
RNA Seq Atlas 103098

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca