InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Zfp385a

Summary

InnateDB Gene

IDBG-189552.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Zfp385a

Gene Name

zinc finger protein 385A

Synonyms

Hzf; Zfp385; Znf385a

Species

Mus musculus

Ensembl Gene

ENSMUSG00000000552

Encoded Proteins

IDBP-626289

zinc finger protein 385A

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161642:
Zinc finger proteins, such as ZNF385A, are regulatory proteins that act as transcription factors, bind single- or double-stranded RNA, or interact with other proteins (Sharma et al., 2004 [PubMed 15527981]).[supplied by OMIM, Oct 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:103313895-103340086

Strand

Reverse strand

Band

Transcripts

ENSMUST00000168828

ENSMUSP00000130176

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002039	p53 binding
GO:0003676	nucleic acid binding
GO:0003730	mRNA 3'-UTR binding
GO:0008270	zinc ion binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006915	apoptotic process
GO:0006974	cellular response to DNA damage stimulus
GO:0007049	cell cycle
GO:0007599	hemostasis
GO:0007611	learning or memory
GO:0007626	locomotory behavior
GO:0008298	intracellular mRNA localization
GO:0010609	mRNA localization resulting in posttranscriptional regulation of gene expression
GO:0030220	platelet formation
GO:0035855	megakaryocyte development
GO:0045600	positive regulation of fat cell differentiation
GO:0070889	platelet alpha granule organization
GO:1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2000765	regulation of cytoplasmic translation

Cellular Component

GO:0000790	nuclear chromatin
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0043025	neuronal cell body

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000161642

View Gene Order

ENSBTAG00000015604

Not yet available

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

KEGG

INOH

PID NCI

p53downstreampathway

Direct p53 effectors

Cross-References

SwissProt

Q8VD12

TrEMBL

UniProt Splice Variant

Entrez Gene

29813

UniGene

Mm.486219

RefSeq

NM_013866 XM_006521053 XM_006521054 XM_006521055 XM_006521056 XM_006521057

OMIM

CCDS

CCDS49743

HPRD

IMGT

MGI ID

MGI:1352495

MGI Symbol

Zfp385a

EMBL

AC164069 AF118566 BC017644 CH466550

GenPept

AAF24093 AAH17644 EDL03923

RNA Seq Atlas

29813