Version 5.4
Mus musculus Gene: Prmt7
Summary
InnateDB Gene IDBG-189811.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prmt7
Gene Name protein arginine N-methyltransferase 7
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000060098
Encoded Proteins
IDBP-189813
protein arginine N-methyltransferase 7
IDBP-262692
protein arginine N-methyltransferase 7
IDBP-262694
protein arginine N-methyltransferase 7
IDBP-536628
protein arginine N-methyltransferase 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132600:
Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing (Miranda et al., 2004 [PubMed 15044439]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:106210936-106252794
Strand Forward strand
Band D3
Transcripts
ENSMUST00000071592 ENSMUSP00000071521
ENSMUST00000109297 ENSMUSP00000104920
ENSMUST00000109296 ENSMUSP00000104919
ENSMUST00000147063
ENSMUST00000128201 ENSMUSP00000119992
ENSMUST00000153272
ENSMUST00000134151
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008276 protein methyltransferase activity
GO:0008469 histone-arginine N-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0016277 [myelin basic protein]-arginine N-methyltransferase activity
GO:0035241 protein-arginine omega-N monomethyltransferase activity
GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity
GO:0035243 protein-arginine omega-N symmetric methyltransferase activity
GO:0043021 ribonucleoprotein complex binding
GO:0044020 histone methyltransferase activity (H4-R3 specific)
Biological Process
GO:0000387 spliceosomal snRNP assembly
GO:0006349 regulation of gene expression by genetic imprinting
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006479 protein methylation
GO:0016571 histone methylation
GO:0018216 peptidyl-arginine methylation
GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine
GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
GO:0030154 cell differentiation
GO:0034969 histone arginine methylation
GO:0043046 DNA methylation involved in gamete generation
GO:0043985 histone H4-R3 methylation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000132600
View Gene Order
ENSBTAG00000009638
Not yet available
Pathways
NETPATH
REACTOME
REACT_218274
Chromatin organization pathway
REACT_202766
Chromatin modifying enzymes pathway
REACT_244207
RMTs methylate histone arginines pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_172623
Chromatin organization pathway
REACT_228108
RMTs methylate histone arginines pathway
REACT_172633
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.251804
RefSeq NM_145404 XM_006530827
OMIM
CCDS CCDS22633
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca