Version 5.4
Mus musculus Gene: St6gal2
Summary
InnateDB Gene IDBG-191090.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol St6gal2
Gene Name beta galactoside alpha 2,6 sialyltransferase 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000024172
Encoded Proteins
IDBP-191092
beta galactoside alpha 2,6 sialyltransferase 2
IDBP-191094
beta galactoside alpha 2,6 sialyltransferase 2
IDBP-541153
beta galactoside alpha 2,6 sialyltransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144057:
This locus encodes a sialyltransferase. The encoded type II transmembrane protein catalyzes the transfer of sialic acid from CMP to an oligosaccharide substrate. Polymorphisms at this locus may be associated with variations in risperidone response in schizophrenic patients. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:55445382-55514581
Strand Forward strand
Band C
Transcripts
ENSMUST00000025000 ENSMUSP00000025000
ENSMUST00000086878 ENSMUSP00000084091
ENSMUST00000133899 ENSMUSP00000120762
ENSMUST00000153220
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity
GO:0008373 sialyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006054 N-acetylneuraminate metabolic process
GO:0006486 protein glycosylation
GO:0009311 oligosaccharide metabolic process
GO:0097503 sialylation
Cellular Component
GO:0005575 cellular_component
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0030173 integral component of Golgi membrane
GO:0032580 Golgi cisterna membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000144057
View Gene Order
ENSBTAG00000000703
Not yet available
Pathways
NETPATH
REACTOME
REACT_248642
Synthesis of substrates in N-glycan biosythesis pathway
REACT_262413
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_237472
Asparagine N-linked glycosylation pathway
REACT_202500
Sialic acid metabolism pathway
KEGG
mmu00510
N-Glycan biosynthesis pathway
mmu00514
Other types of O-glycan biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22433
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_22387
Synthesis of substrates in N-glycan biosythesis pathway
REACT_200874
Sialic acid metabolism pathway
REACT_17015
Metabolism of proteins pathway
REACT_223866
Asparagine N-linked glycosylation pathway
REACT_213782
Metabolism of proteins pathway
REACT_214405
Post-translational protein modification pathway
REACT_213420
Sialic acid metabolism pathway
REACT_220681
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_226954
Synthesis of substrates in N-glycan biosythesis pathway
KEGG
hsa00510
N-Glycan biosynthesis pathway
hsa00514
Other types of O-glycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q76K27
TrEMBL A9C433 B2RQY9
UniProt Splice Variant
Entrez Gene 240119
UniGene Mm.311687
RefSeq NM_172829 XM_006524266 XM_006524267 XM_006524268 XM_006524269 XM_006524270 XM_006544953 XM_006544954 XM_006544955 XM_006544956 XM_006544957
OMIM
CCDS CCDS28886
HPRD
IMGT
MGI ID MGI:2445190
MGI Symbol St6gal2
EMBL AB095093 AK082566 AK129462 BC125586 BC138142 CT009635
GenPept AAI25587 AAI38143 BAC38534 BAC87752 BAC98272 CAP19181 CAP19182
RNA Seq Atlas 240119

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca