Mus musculus Gene: Avpr1b | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-191336.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Avpr1b | ||||||
Gene Name | arginine vasopressin receptor 1B | ||||||
Synonyms | AVPR3; V3/V1b; VIBR; VPR3 | ||||||
Species | Mus musculus | ||||||
Ensembl Gene | ENSMUSG00000026432 | ||||||
Encoded Proteins |
arginine vasopressin receptor 1B
arginine vasopressin receptor 1B
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198049:
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 1:131599239-131612000 | ||||||
Strand | Forward strand | ||||||
Band | E4 | ||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||
NETPATH | |||||||
REACTOME |
Vasopressin-like receptors pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
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KEGG |
Calcium signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
Vascular smooth muscle contraction pathway
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INOH | |||||||
PID NCI | |||||||
Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Vasopressin-like receptors pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
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KEGG |
Neuroactive ligand-receptor interaction pathway
Calcium signaling pathway pathway
Vascular smooth muscle contraction pathway
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INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | |||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | |||||||
UniGene | |||||||
RefSeq | NM_011924 | ||||||
OMIM | |||||||
CCDS | CCDS35703 | ||||||
HPRD | |||||||
IMGT | |||||||
MGI ID | |||||||
MGI Symbol | |||||||
EMBL | |||||||
GenPept | |||||||
RNA Seq Atlas | |||||||