Mus musculus Gene: Cct2 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-191542.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Cct2 | ||||||||||||||||||||||
Gene Name | chaperonin containing Tcp1, subunit 2 (beta) | ||||||||||||||||||||||
Synonyms | Cctb | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000034024 | ||||||||||||||||||||||
Encoded Proteins |
chaperonin containing Tcp1, subunit 2 (beta)
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166226:
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 10:117050998-117063814 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | D2 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 113 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Chaperonin-mediated protein folding pathway
Association of TriC/CCT with target proteins during biosynthesis pathway
Folding of actin by CCT/TriC pathway
Metabolism of proteins pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
Protein folding pathway
Formation of tubulin folding intermediates by CCT/TriC pathway
Prefoldin mediated transfer of substrate to CCT/TriC pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Association of TriC/CCT with target proteins during biosynthesis pathway
Folding of actin by CCT/TriC pathway
Prefoldin mediated transfer of substrate to CCT/TriC pathway
Formation of tubulin folding intermediates by CCT/TriC pathway
Protein folding pathway
Chaperonin-mediated protein folding pathway
Metabolism of proteins pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
Prefoldin mediated transfer of substrate to CCT/TriC pathway
Folding of actin by CCT/TriC pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
Chaperonin-mediated protein folding pathway
Metabolism of proteins pathway
Protein folding pathway
Association of TriC/CCT with target proteins during biosynthesis pathway
Formation of tubulin folding intermediates by CCT/TriC pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | P80314 | ||||||||||||||||||||||
TrEMBL | Q542X7 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 12461 | ||||||||||||||||||||||
UniGene | Mm.247788 | ||||||||||||||||||||||
RefSeq | NM_007636 XM_006513161 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS36067 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:107186 | ||||||||||||||||||||||
MGI Symbol | Cct2 | ||||||||||||||||||||||
EMBL | AB022156 AK075581 AK145406 AK166891 BC007470 BC026918 CH466539 Z31553 | ||||||||||||||||||||||
GenPept | AAH07470 AAH26918 BAA81874 BAC35834 BAE26419 BAE39096 CAA83428 EDL21824 | ||||||||||||||||||||||
RNA Seq Atlas | 12461 | ||||||||||||||||||||||