Version 5.4
Mus musculus Gene: Myoz2
Summary
InnateDB Gene IDBG-192048.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myoz2
Gene Name myozenin 2
Synonyms 1110012I24Rik; Fatz-2; Myozl2
Species Mus musculus
Ensembl Gene ENSMUSG00000028116
Encoded Proteins
IDBP-192050
myozenin 2
IDBP-539394
myozenin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172399:
The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:123006206-123034990
Strand Reverse strand
Band G1
Transcripts
ENSMUST00000029761 ENSMUSP00000029761
ENSMUST00000143464
ENSMUST00000141588 ENSMUSP00000115450
ENSMUST00000140231
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0031433 telethonin binding
Biological Process
Cellular Component
GO:0015629 actin cytoskeleton
GO:0030018 Z disc
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000172399
View Gene Order
ENSBTAG00000002574
Not yet available
Cross-References
SwissProt Q9JJW5
TrEMBL
UniProt Splice Variant
Entrez Gene 59006
UniGene
RefSeq NM_021503
OMIM
CCDS CCDS17816
HPRD
IMGT
MGI ID MGI:1913063
MGI Symbol Myoz2
EMBL AJ252148 AY013296 BC024360
GenPept AAG38939 AAH24360 CAB92972
RNA Seq Atlas 59006

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca