InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cntn2

Summary

InnateDB Gene

IDBG-192095.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cntn2

Gene Name

contactin 2

Synonyms

D130012K04Rik; TAG-1; Tax

Species

Mus musculus

Ensembl Gene

ENSMUSG00000053024

Encoded Proteins

IDBP-192097

contactin 2

IDBP-789350

contactin 2

IDBP-789351

contactin 2

IDBP-789355

contactin 2

IDBP-789357

contactin 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184144:
The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:132509427-132543256

Strand

Reverse strand

Band

Transcripts

ENSMUST00000086521	ENSMUSP00000083707
ENSMUST00000189528	ENSMUSP00000141179
ENSMUST00000188065	ENSMUSP00000140306
ENSMUST00000186487
ENSMUST00000190601
ENSMUST00000188143
ENSMUST00000188943	ENSMUSP00000139795
ENSMUST00000186530	ENSMUSP00000139897

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	33 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001948	glycoprotein binding
GO:0005515	protein binding
GO:0030246	carbohydrate binding
GO:0043621	protein self-association

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0001764	neuron migration
GO:0007155	cell adhesion
GO:0007411	axon guidance
GO:0007413	axonal fasciculation
GO:0007612	learning
GO:0007628	adult walking behavior
GO:0010769	regulation of cell morphogenesis involved in differentiation
GO:0010954	positive regulation of protein processing
GO:0021853	cerebral cortex GABAergic interneuron migration
GO:0022010	central nervous system myelination
GO:0031133	regulation of axon diameter
GO:0031175	neuron projection development
GO:0031623	receptor internalization
GO:0034613	cellular protein localization
GO:0045163	clustering of voltage-gated potassium channels
GO:0045665	negative regulation of neuron differentiation
GO:0048168	regulation of neuronal synaptic plasticity
GO:0048710	regulation of astrocyte differentiation
GO:0060168	positive regulation of adenosine receptor signaling pathway
GO:0071205	protein localization to juxtaparanode region of axon
GO:0071206	establishment of protein localization to juxtaparanode region of axon
GO:0097090	presynaptic membrane organization

Cellular Component

GO:0008076	voltage-gated potassium channel complex
GO:0009986	cell surface
GO:0030424	axon
GO:0031225	anchored component of membrane
GO:0033268	node of Ranvier
GO:0043005	neuron projection
GO:0043025	neuronal cell body
GO:0043209	myelin sheath
GO:0044224	juxtaparanode region of axon