Version 5.4
Mus musculus Gene: Fabp3
Summary
InnateDB Gene IDBG-192674.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fabp3
Gene Name fatty acid binding protein 3, muscle and heart
Synonyms Fabph-1; Fabph-4; Fabph1; Fabph4; H-FABP; Mdgi
Species Mus musculus
Ensembl Gene ENSMUSG00000028773
Encoded Proteins
IDBP-192676
fatty acid binding protein 3, muscle and heart
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121769:
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:130308595-130315463
Strand Forward strand
Band D2.2
Transcripts
ENSMUST00000070532 ENSMUSP00000070709
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0008289 lipid binding
Biological Process
GO:0042632 cholesterol homeostasis
GO:0044539 long-chain fatty acid import
GO:0046320 regulation of fatty acid oxidation
GO:0055091 phospholipid homeostasis
GO:0071073 positive regulation of phospholipid biosynthetic process
GO:2001245 regulation of phosphatidylcholine biosynthetic process
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000121769
View Gene Order
ENSBTAG00000016819
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03320
PPAR signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03320
PPAR signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt P11404
TrEMBL Q5EBJ0
UniProt Splice Variant
Entrez Gene 14077
UniGene
RefSeq NM_010174
OMIM
CCDS CCDS18709
HPRD
IMGT
MGI ID MGI:95476
MGI Symbol Fabp3
EMBL AK142156 BC002082 BC089542 CH466552 U02883 U02884 X14961
GenPept AAA03445 AAA61933 AAH02082 AAH89542 BAE24952 CAA33084 EDL30140
RNA Seq Atlas 14077

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca