Version 5.4
Mus musculus Gene: Xpot
Summary
InnateDB Gene IDBG-192955.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Xpot
Gene Name exportin, tRNA (nuclear export receptor for tRNAs)
Synonyms 1110004L07Rik; 3110065H13Rik; AI452076; C79645; EXPORTIN-T
Species Mus musculus
Ensembl Gene ENSMUSG00000034667
Encoded Proteins
IDBP-192957
exportin, tRNA (nuclear export receptor for tRNAs)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184575:
This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:121587380-121626316
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000039810 ENSMUSP00000043488
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0005488 binding
GO:0008536 Ran GTPase binding
Biological Process
GO:0006409 tRNA export from nucleus
GO:0006886 intracellular protein transport
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000184575
View Gene Order
ENSBTAG00000026962
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03013
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt Q9CRT8
TrEMBL
UniProt Splice Variant
Entrez Gene 73192
UniGene Mm.25042 Mm.413364 Mm.487930
RefSeq NM_001081056 XM_006514204 XM_006514205 XM_006514206 XM_006514208
OMIM
CCDS
HPRD
IMGT
MGI ID MGI:1920442
MGI Symbol Xpot
EMBL AC124992 AK014235 BC094337
GenPept AAH94337 BAB29220
RNA Seq Atlas 73192

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca