Version 5.4
Mus musculus Gene: Mecr
Summary
InnateDB Gene IDBG-193276.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mecr
Gene Name mitochondrial trans-2-enoyl-CoA reductase
Synonyms AI195831; Nrbf1
Species Mus musculus
Ensembl Gene ENSMUSG00000028910
Encoded Proteins
IDBP-193278
mitochondrial trans-2-enoyl-CoA reductase
IDBP-536980
mitochondrial trans-2-enoyl-CoA reductase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116353:
Gene Information
Type Protein coding
Genomic Location Chromosome 4:131843470-131867786
Strand Forward strand
Band D2.3
Transcripts
ENSMUST00000030742 ENSMUSP00000030742
ENSMUST00000137321 ENSMUSP00000114543
ENSMUST00000139573
ENSMUST00000142386
ENSMUST00000128116
ENSMUST00000145045
ENSMUST00000127735
ENSMUST00000143067
ENSMUST00000137412
ENSMUST00000128607
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
GO:0016922 ligand-dependent nuclear receptor binding
GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006633 fatty acid biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000116353
View Gene Order
ENSBTAG00000017253
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00062
Fatty acid elongation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00062
Fatty acid elongation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.192706
RefSeq NM_025297
OMIM
CCDS CCDS18715
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca