Version 5.4
| Mus musculus Gene: Pla2g12a | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-193763.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Pla2g12a | ||||||||
| Gene Name | phospholipase A2, group XIIA | ||||||||
| Synonyms | 2310004B05Rik; GXII; GXII-1; GXII-1-PLA2; mGXII-1; Pla2g12; Rossy | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000027999 | ||||||||
| Encoded Proteins |
phospholipase A2, group XIIA
phospholipase A2, group XIIA
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123739:
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 3:129878622-129895821 | ||||||||
| Strand | Forward strand | ||||||||
| Band | G3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Acyl chain remodelling of PC pathway
Acyl chain remodelling of PG pathway
Acyl chain remodelling of PS pathway
Acyl chain remodelling of PE pathway
Acyl chain remodelling of PI pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Synthesis of PA pathway
Phospholipid metabolism pathway
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| KEGG |
Glycerophospholipid metabolism pathway
Arachidonic acid metabolism pathway
Ether lipid metabolism pathway
Linoleic acid metabolism pathway
alpha-Linolenic acid metabolism pathway
Vascular smooth muscle contraction pathway
Pancreatic secretion pathway
Fat digestion and absorption pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Acyl chain remodelling of PC pathway
Acyl chain remodelling of PI pathway
Acyl chain remodelling of PS pathway
Synthesis of PA pathway
Acyl chain remodelling of PG pathway
Acyl chain remodelling of PE pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
Metabolism pathway
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| KEGG |
alpha-Linolenic acid metabolism pathway
Arachidonic acid metabolism pathway
Glycerophospholipid metabolism pathway
Linoleic acid metabolism pathway
Ether lipid metabolism pathway
Vascular smooth muscle contraction pathway
Fat digestion and absorption pathway
Pancreatic secretion pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9EPR2 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 66350 | ||||||||
| UniGene | Mm.151951 Mm.468799 | ||||||||
| RefSeq | NM_023196 NM_183423 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS17836 CCDS17837 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1913600 | ||||||||
| MGI Symbol | Pla2g12a | ||||||||
| EMBL | AK003183 AK009133 AK010011 AK010174 AK163693 AY007381 AY007382 BC051117 | ||||||||
| GenPept | AAG23336 AAG23337 AAH51117 BAB26094 BAB26641 BAB26747 BAE37460 | ||||||||
| RNA Seq Atlas | 66350 | ||||||||