InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Sec24b

Summary

InnateDB Gene

IDBG-193903.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sec24b

Gene Name

Sec24 related gene family, member B (S. cerevisiae)

Synonyms

AI605202; SEC24

Species

Mus musculus

Ensembl Gene

ENSMUSG00000001052

Encoded Proteins

IDBP-193905

Sec24 related gene family, member B (S. cerevisiae)

IDBP-620744

Sec24 related gene family, member B (S. cerevisiae)

IDBP-620746

Sec24 related gene family, member B (S. cerevisiae)

IDBP-620747

Sec24 related gene family, member B (S. cerevisiae)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138802:
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The role of this gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:129982759-130061553

Strand

Reverse strand

Band

Transcripts

ENSMUST00000001079	ENSMUSP00000001079
ENSMUST00000170163
ENSMUST00000164758
ENSMUST00000172324
ENSMUST00000165873	ENSMUSP00000132861
ENSMUST00000165889
ENSMUST00000168644	ENSMUSP00000126923
ENSMUST00000168908
ENSMUST00000168675	ENSMUSP00000132632

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0001843	neural tube closure
GO:0002093	auditory receptor cell morphogenesis
GO:0003151	outflow tract morphogenesis
GO:0006886	intracellular protein transport
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0021747	cochlear nucleus development
GO:0035909	aorta morphogenesis
GO:0060088	auditory receptor cell stereocilium organization
GO:0060425	lung morphogenesis
GO:0060463	lung lobe morphogenesis
GO:0060982	coronary artery morphogenesis
GO:0061156	pulmonary artery morphogenesis
GO:0072358	cardiovascular system development
GO:0090178	regulation of establishment of planar polarity involved in neural tube closure
GO:1901301	regulation of cargo loading into COPII-coated vesicle