Version 5.4
| Homo sapiens Gene: TAS2R8 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-19441.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | TAS2R8 | ||||||||
| Gene Name | taste receptor, type 2, member 8 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Gene | ENSG00000121314 | ||||||||
| Encoded Proteins |
taste receptor, type 2, member 8
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 12:10806051-10807293 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | p13.2 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
| No orthologs found for this gene | |||||||||
| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
G alpha (i) signalling events pathway
Class C/3 (Metabotropic glutamate/pheromone receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
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| KEGG |
Taste transduction pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9NYW2 | ||||||||
| TrEMBL | Q50KU1 Q50KU2 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 50836 | ||||||||
| UniGene | Hs.533755 | ||||||||
| RefSeq | NM_023918 | ||||||||
| HUGO | HGNC:14915 | ||||||||
| OMIM | 604794 | ||||||||
| CCDS | CCDS8632 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AB199051 AB199052 AB199053 AF227134 AY724935 BC069084 BC069551 BC096701 BC096735 BC098353 | ||||||||
| GenPept | AAF43907 AAH69084 AAH69551 AAH96701 AAH96735 AAH98353 AAU21137 BAD97955 BAD97956 BAD97957 | ||||||||
| RNA Seq Atlas | 50836 | ||||||||