Mus musculus Gene: Pld2 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-194655.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Pld2 | ||||||||||||
Gene Name | phospholipase D2 | ||||||||||||
Synonyms | |||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Gene | ENSMUSG00000020828 | ||||||||||||
Encoded Proteins |
phospholipase D2
phospholipase D2
phospholipase D2
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129219:
The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 11:70540064-70558110 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | B3 | ||||||||||||
Transcripts | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Innate Immune System pathway
Synthesis of PG pathway
Role of phospholipids in phagocytosis pathway
Metabolism pathway
Immune System pathway
Metabolism of lipids and lipoproteins pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Glycerophospholipid biosynthesis pathway
Synthesis of PA pathway
Phospholipid metabolism pathway
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KEGG |
Glycerophospholipid metabolism pathway
Ether lipid metabolism pathway
GnRH signaling pathway pathway
Fc gamma R-mediated phagocytosis pathway
Endocytosis pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH |
EGFR1 pathway
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REACTOME |
Role of phospholipids in phagocytosis pathway
Synthesis of PA pathway
Synthesis of PG pathway
Metabolism of lipids and lipoproteins pathway
Innate Immune System pathway
Glycerophospholipid biosynthesis pathway
Immune System pathway
Phospholipid metabolism pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Metabolism pathway
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KEGG |
GnRH signaling pathway pathway
Glycerophospholipid metabolism pathway
Ether lipid metabolism pathway
Fc gamma R-mediated phagocytosis pathway
Endocytosis pathway
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INOH | |||||||||||||
PID NCI |
Alpha-synuclein signaling
IL8- and CXCR2-mediated signaling events
LPA receptor mediated events
ErbB1 downstream signaling
Arf1 pathway
Angiopoietin receptor Tie2-mediated signaling
Fc-epsilon receptor I signaling in mast cells
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Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | |||||||||||||
UniGene | Mm.260177 Mm.398583 | ||||||||||||
RefSeq | NM_008876 XM_006532483 XM_006532484 XM_006537136 XM_006537137 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS24953 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
MGI ID | |||||||||||||
MGI Symbol | |||||||||||||
EMBL | |||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | |||||||||||||