Version 5.4
Mus musculus Gene: Vps33b
Summary
InnateDB Gene IDBG-194838.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vps33b
Gene Name vacuolar protein sorting 33B (yeast)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000030534
Encoded Proteins
IDBP-194840
vacuolar protein sorting 33B (yeast)
IDBP-788636
vacuolar protein sorting 33B (yeast)
IDBP-788641
vacuolar protein sorting 33B (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184056:
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:80269649-80291579
Strand Forward strand
Band D2
Transcripts
ENSMUST00000032749 ENSMUSP00000032749
ENSMUST00000150585 ENSMUSP00000138224
ENSMUST00000128254
ENSMUST00000135053 ENSMUSP00000138472
ENSMUST00000145594
ENSMUST00000135470
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006904 vesicle docking involved in exocytosis
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0032400 melanosome localization
GO:0032418 lysosome localization
GO:0061025 membrane fusion
GO:0070889 platelet alpha granule organization
Cellular Component
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005770 late endosome
GO:0030897 HOPS complex
GO:0031091 platelet alpha granule
GO:0031902 late endosome membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000184056
View Gene Order
ENSBTAG00000000026
Not yet available
Cross-References
SwissProt
TrEMBL S4R1H4
UniProt Splice Variant
Entrez Gene 233405
UniGene
RefSeq XM_006540850 NM_178070 XM_006540849 XM_006540851 XM_006540852
OMIM
CCDS CCDS39997
HPRD
IMGT
MGI ID MGI:2446237
MGI Symbol Vps33b
EMBL AC109232
GenPept
RNA Seq Atlas 233405

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca