Mus musculus Gene: Elp4
Summary
InnateDB Gene IDBG-195192.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Elp4
Gene Name elongation protein 4 homolog (S. cerevisiae)
Synonyms A330107A17Rik; Paxneb
Species Mus musculus
Ensembl Gene ENSMUSG00000027167
Encoded Proteins
elongation protein 4 homolog (S. cerevisiae)
elongation protein 4 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109911:
This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:105701027-105904564
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000028588 ENSMUSP00000028588
ENSMUST00000122965 ENSMUSP00000116575
ENSMUST00000152272
ENSMUST00000148441
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004402 histone acetyltransferase activity
GO:0008607 phosphorylase kinase regulator activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0016573 histone acetylation
GO:0045859 regulation of protein kinase activity
Cellular Component
GO:0005737 cytoplasm
GO:0008023 transcription elongation factor complex
GO:0016591 DNA-directed RNA polymerase II, holoenzyme
GO:0033588 Elongator holoenzyme complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Chromatin organization pathway
HATs acetylate histones pathway
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
HATs acetylate histones pathway
Chromatin organization pathway
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.33870 Mm.401814 Mm.412437 Mm.462598
RefSeq NM_023876
OMIM
CCDS CCDS16500
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas