Version 5.4
Mus musculus Gene: Med13l
Summary
InnateDB Gene IDBG-195258.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Med13l
Gene Name mediator complex subunit 13-like
Synonyms 2210413I17Rik; 6330591G05Rik; 9030618F05Rik; mKIAA1025; Thrap2; Trap240L
Species Mus musculus
Ensembl Gene ENSMUSG00000018076
Encoded Proteins
IDBP-195260
mediator complex subunit 13-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123066:
The protein encoded by this gene is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).[provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:118560719-118765435
Strand Forward strand
Band F
Transcripts
ENSMUST00000100816 ENSMUSP00000098379
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0003674 molecular_function
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0016592 mediator complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000123066
View Gene Order
ENSBTAG00000001888
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_116145
PPARA activates gene expression pathway
REACT_19241
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_27161
Transcriptional regulation of white adipocyte differentiation pathway
REACT_111045
Developmental Biology pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9QLJ3
UniProt Splice Variant
Entrez Gene 76199
UniGene Mm.206238 Mm.471939
RefSeq NM_172424
OMIM
CCDS CCDS57375
HPRD
IMGT
MGI ID MGI:2670178
MGI Symbol Med13l
EMBL AC117585 AC129552
GenPept
RNA Seq Atlas 76199

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca