Version 5.4
Mus musculus Gene: Pik3r4
Summary
InnateDB Gene IDBG-195461.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pik3r4
Gene Name phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
Synonyms 2210010O15Rik; C730038E05Rik; C85833; D9Ertd418e
Species Mus musculus
Ensembl Gene ENSMUSG00000032571
Encoded Proteins
IDBP-195463
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
IDBP-790066
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
IDBP-790067
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
IDBP-790068
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
IDBP-790069
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196455:
Gene Information
Type Protein coding
Genomic Location Chromosome 9:105642978-105687657
Strand Forward strand
Band F1
Transcripts
ENSMUST00000065778 ENSMUSP00000067400
ENSMUST00000187573
ENSMUST00000190358 ENSMUSP00000139643
ENSMUST00000191117
ENSMUST00000187446
ENSMUST00000191268 ENSMUSP00000139427
ENSMUST00000188784 ENSMUSP00000140988
ENSMUST00000186943 ENSMUSP00000140311
ENSMUST00000188385
ENSMUST00000189691
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
GO:0005770 late endosome
GO:0005930 axoneme
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196455
View Gene Order
ENSBTAG00000020787
Not yet available
Pathways
NETPATH
REACTOME
REACT_239142
Innate Immune System pathway
REACT_198975
Synthesis of PIPs at the early endosome membrane pathway
REACT_198972
Synthesis of PIPs at the late endosome membrane pathway
REACT_198970
Synthesis of PIPs at the Golgi membrane pathway
REACT_240250
Signaling by Insulin receptor pathway
REACT_199016
PI Metabolism pathway
REACT_188937
Metabolism pathway
REACT_230745
Immune System pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_249409
Toll Like Receptor 9 (TLR9) Cascade pathway
REACT_259732
Insulin receptor signalling cascade pathway
REACT_188215
IRS-related events triggered by IGF1R pathway
REACT_188218
IGF1R signaling cascade pathway
REACT_188219
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
REACT_240139
PI3K Cascade pathway
REACT_251547
Toll-Like Receptors Cascades pathway
REACT_188643
Phospholipid metabolism pathway
REACT_243154
IRS-related events pathway
REACT_242206
IRS-mediated signalling pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04140
Regulation of autophagy pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_9047
Toll Like Receptor 9 (TLR9) Cascade pathway
REACT_976
PI3K Cascade pathway
REACT_498
Signaling by Insulin receptor pathway
REACT_150203
IRS-related events triggered by IGF1R pathway
REACT_150359
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
REACT_120756
Synthesis of PIPs at the early endosome membrane pathway
REACT_120836
Synthesis of PIPs at the Golgi membrane pathway
REACT_120918
Synthesis of PIPs at the late endosome membrane pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_6802
Innate Immune System pathway
REACT_6966
Toll-Like Receptors Cascades pathway
REACT_111102
Signal Transduction pathway
REACT_332
IRS-mediated signalling pathway
REACT_6900
Immune System pathway
REACT_1195
Insulin receptor signalling cascade pathway
REACT_121175
PI Metabolism pathway
REACT_120870
Phospholipid metabolism pathway
REACT_762
IRS-related events pathway
REACT_150210
IGF1R signaling cascade pathway
REACT_111217
Metabolism pathway
KEGG
hsa04140
Regulation of autophagy pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001081309
OMIM
CCDS CCDS40753
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca