Version 5.4
Mus musculus Gene: Lin28a
Summary
InnateDB Gene IDBG-195575.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lin28a
Gene Name lin-28 homolog A (C. elegans)
Synonyms AL024421; ENSMUSG00000070700; Gm10299; Lin-28; lin-28A; Lin28; Tex17
Species Mus musculus
Ensembl Gene ENSMUSG00000050966
Encoded Proteins
IDBP-195577
lin-28 homolog A (C. elegans)
IDBP-719203
IDBP-718955
IDBP-718860
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131914:
Gene Information
Type Protein coding
Genomic Location Chromosome 4:134003330-134018841
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000051674 ENSMUSP00000050488
ENSMUST00000176897 ENSMUSP00000135736
ENSMUST00000176292 ENSMUSP00000135608
ENSMUST00000176113 ENSMUSP00000135254
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 17 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0031369 translation initiation factor binding
GO:0035198 miRNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0007281 germ cell development
GO:0010586 miRNA metabolic process
GO:0010587 miRNA catabolic process
GO:0019827 stem cell maintenance
GO:0031054 pre-miRNA processing
GO:0031123 RNA 3'-end processing
GO:0045666 positive regulation of neuron differentiation
GO:0045686 negative regulation of glial cell differentiation
GO:0045727 positive regulation of translation
GO:0048863 stem cell differentiation
GO:0060964 regulation of gene silencing by miRNA
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0010494 cytoplasmic stress granule
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000131914
View Gene Order
ENSBTAG00000040497
Not yet available
Pathways
NETPATH
REACTOME
REACT_216222
Transcriptional regulation of pluripotent stem cells pathway
REACT_188576
Developmental Biology pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_111045
Developmental Biology pathway
REACT_200812
Transcriptional regulation of pluripotent stem cells pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.302567 Mm.419331 Mm.421761
RefSeq NM_145833 XM_006539317
OMIM
CCDS CCDS18761
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca