Version 5.4
Mus musculus Gene: Bank1
Summary
InnateDB Gene IDBG-195709.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bank1
Gene Name B cell scaffold protein with ankyrin repeats 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037922
Encoded Proteins
IDBP-195711
B-cell scaffold protein with ankyrin repeats 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000153064:
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:136053363-136326046
Strand Reverse strand
Band G3
Transcripts
ENSMUST00000041577 ENSMUSP00000035484
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0042113 B cell activation
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000153064
View Gene Order
ENSBTAG00000015297
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_12
BCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.418570
RefSeq NM_001033350 XM_006501483 XM_006501484 XM_006501485
OMIM
CCDS CCDS38645
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca