Version 5.4
Mus musculus Gene: Mis12
Summary
InnateDB Gene IDBG-195870.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mis12
Gene Name MIS12 homolog (yeast)
Synonyms 2510025F08Rik; AU044651; Misc12
Species Mus musculus
Ensembl Gene ENSMUSG00000040599
Encoded Proteins
IDBP-195872
MIS12 homolog (yeast)
IDBP-533865
MIS12 homolog (yeast)
IDBP-532756
MIS12 homolog (yeast)
IDBP-531868
MIS12 homolog (yeast)
IDBP-540078
MIS12 homolog (yeast)
IDBP-625242
MIS12 homolog (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167842:
Gene Information
Type Protein coding
Genomic Location Chromosome 11:71019611-71027371
Strand Forward strand
Band B4
Transcripts
ENSMUST00000048807 ENSMUSP00000039500
ENSMUST00000133413 ENSMUSP00000123291
ENSMUST00000155236 ENSMUSP00000116762
ENSMUST00000143762 ENSMUSP00000115256
ENSMUST00000136137 ENSMUSP00000121057
ENSMUST00000164220 ENSMUSP00000127782
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007049 cell cycle
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0051382 kinetochore assembly
Cellular Component
GO:0000444 MIS12/MIND type complex
GO:0000775 chromosome, centromeric region
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000167842
View Gene Order
ENSBTAG00000020432
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_207679
Separation of Sister Chromatids pathway
REACT_198961
Resolution of Sister Chromatid Cohesion pathway
REACT_188804
Cell Cycle pathway
REACT_241408
M Phase pathway
REACT_199403
Mitotic Metaphase and Anaphase pathway
REACT_256756
Mitotic Prometaphase pathway
REACT_202512
Mitotic Anaphase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
REACT_216366
M Phase pathway
REACT_212887
Separation of Sister Chromatids pathway
REACT_215084
Mitotic Metaphase and Anaphase pathway
REACT_211185
Mitotic Anaphase pathway
REACT_215505
Cell Cycle, Mitotic pathway
REACT_214934
Cell Cycle pathway
REACT_209545
Resolution of Sister Chromatid Cohesion pathway
REACT_203101
Mitotic Prometaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.28227 Mm.427769 Mm.475587
RefSeq NM_025993 XM_006533968 XM_006537203
OMIM
CCDS CCDS24973
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca