Version 5.4
Mus musculus Gene: Nek7
Summary
InnateDB Gene IDBG-196023.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nek7
Gene Name NIMA (never in mitosis gene a)-related expressed kinase 7
Synonyms 2810460C19Rik; AU020186
Species Mus musculus
Ensembl Gene ENSMUSG00000026393
Encoded Proteins
IDBP-196025
NIMA (never in mitosis gene a)-related expressed kinase 7
IDBP-789526
NIMA (never in mitosis gene a)-related expressed kinase 7
IDBP-789527
NIMA (never in mitosis gene a)-related expressed kinase 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151414:
NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.[supplied by OMIM, Jul 2002]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:138483837-138620218
Strand Reverse strand
Band E4
Transcripts
ENSMUST00000027642 ENSMUSP00000027642
ENSMUST00000187407 ENSMUSP00000140635
ENSMUST00000186017 ENSMUSP00000140903
ENSMUST00000191549
ENSMUST00000188820
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000151414
View Gene Order
ENSBTAG00000016943
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160122
Activation of NIMA Kinases NEK9, NEK6, NEK7 pathway
REACT_163931
Nuclear Pore Complex (NPC) Disassembly pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_765
Mitotic Prophase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_160255
Nuclear Envelope Breakdown pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_021605
OMIM
CCDS CCDS15332
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca